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Enhancing PP2A activity would decrease tau hyper-phosphorylation in Alzheimer Disease.


Therapeutic benefits of a component of coffee in a rat model of Alzheimer's Disease.


Among the phosphatases, which regulate the phosphorylation of tau, PP2A, the activity of which is down-regulated in Alzheimer’s Diseased brain, is by far the major enzyme.


Downregulation of PP2A carboxyl methylation and methyltransferase may contribute to Alzheimer Disease pathogenesis.


Altered expression levels of the PP2A ABalphaC enzyme are associated with Alzheimer Disease pathology. 


The down-regulation of PP2A activity is thought to play an important role in the formation of tau hyperphosphorylation in the Alzheimer's diseased brain.


PP2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation.


PP2A: a novel druggable target for Alzheimer's disease.


Deficiencies in phosphatase methylation play an important role in the etiology of Alzheimer's disease.


PP2A methylation: a link between elevated plasma homocysteine and Alzheimer's Disease.


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